There were fifteen studies with a low potential for bias, three with a moderate potential for bias, and seven with a high potential for bias. ResultsĪ total of twenty-six papers were included in the qualitative synthesis, with twenty-two of them being included in the meta-analysis.
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The RevMan software was used to perform a meta-analysis of the pooled data and subgroups according to the technique of anaesthetic solution delivery, as well as a sensitivity analysis ( P < 0.05). The Cochrane Collaboration Tool and the Minors checklist were used to assess the quality of the selected studies for randomised controlled trials (RCTs) and non-randomised studies, respectively. Two reviewers critically evaluated the papers for inclusion and exclusion criteria, and data extraction was done on the selected publications.
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A manual search of the reference lists of the publications found was also carried out. PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, Google Scholar, and Open Gray were used to conduct a thorough literature search. 2% Lidocaine for mandibular and maxillary block and infiltration anaesthesia in patients with irreversible pulpitis (IP). The goal of this systematic review and meta-analysis is to determine the performance of 4% Articaine vs.
Efficacy of 4% articaine vs 2% lidocaine in mandibular and maxillary block and infiltration anaesthesia in patients with irreversible pulpitis: a systematic review and meta-analysis. Cite this article Miglani S, Ansari I, Patro S, Mohanty A, Mansoori S, Ahuja B, Karobari MI, Shetty KP, Saeed MH, Luke AM, Pawar AM. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. Licence This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed.
9 Department of Conservative Dentistry & Endodontics, Nair Hospital Dental College, Mumbai, Maharashtra, India, Mumbai, India DOI 10.7717/peerj.12214 Published Accepted Received Academic Editor Luca Testarelli Subject Areas Dentistry Keywords Articaine, Irreversible pulpitis, Lidocaine, Meta-analysis, Sensitivity analysis, Success rate Copyright © 2021 Miglani et al.
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